MT-1 10 mg — synthetic analogue of α-MSH
Le MT-1, also calledMelanotan 1or afamelanotide, is asynthetic analogue of the α-MSH hormone(melanotropic hormone), the endogenous peptide that activates the melanogenesis pathway. Its modified structure makes it significantly more stable than natural α-MSH, whose half-life is measured in minutes—this stability makes it a usable tool in the laboratory. Molecular mass of approximately 1,646 g/mol. Bottle of10 mg lyophilizedintendedexclusively for laboratory research.
Product features
- Compound :MT-1 / Melanotan 1 (afamelanotide), α-MSH analogue
- Quantity :10 mg per vial, lyophilized
- Purity:controlled by HPLC, result on the batch certificate
- Quality control:Independent COA per batch
- Presentation :sealed bottle, crimped cap, white lyophilized powder
Scientific context
The MT-1 is amelanocortin receptor agonist, with a marked affinity for theMC1R, the receptor expressed on the surface of melanocytes. Published work focuses primarily on themelanogenesis pathwaystudied in cell culture: receptor binding, cAMP cascade, tyrosinase expression.
It is a research compoundwell characterized pharmacologically— its target and mechanism are documented — but that says nothing about its safety outside of a laboratory setting.
MT-1 and MT-2: two analogues that are not interchangeable
Both references are in the catalog and are often confused. They differ on the most important point, thereceptor selectivity :
- MT-1— linear, ~1646 g/mol, affinity mainly directed towards theMC1RNarrower profile.
- MT-2— cyclic, ~1024 g/mol, agonistnon-selectiveIt also activates MC3R and MC4R, two receptors involved in other physiological pathways. Broader profile, and therefore more off-target effects in the models studied.
A protocol designed for one cannot be transposed to the other: neither molar mass, nor selectivity, nor stability overlap.
Reconstruction and conservation
The bottle contains a freeze-dried powder to be reconstituted withbacteriostatic water, available separately. Powder should be stored away from light; reconstituted solution should be stored in the refrigerator. Melanocortin analogues arelight-sensitive: limit the exposure of the reconstituted vial.
Quality and analysis
Each batch is analyzed byHPLCwith aIndependent Certificate of Analysis (COA)specific to the batch. The purity is that indicated on the certificate.
Delivery
Shipping within 24 to 48 hours from our stock in France.3 to 5 business days, with follow-up. Direct sale without intermediaries — that's what allows the advertised price.
What this product is not
The MT-1 issold here as a laboratory reagent, and nothing elseThis is notneither a medicine, nor a cosmetic, nor a tanning productHe is notnot intended for human or veterinary useThis product is not intended for diagnostic or therapeutic use, and no instructions for use, dosage, or administration protocol are provided. The buyer is solely responsible for complying with applicable regulations in their country.
Frequently Asked Questions
What is the MT-1?
MT-1 (Melanotan 1, afamelanotide) is a synthetic analogue of the hormone α-MSH, studied in research as an agonist of melanocortin receptors, primarily the MC1R.
What is the difference with the MT-2?
Selectivity. MT-1 is linear (~1646 g/mol) and primarily targets MC1R; MT-2 is cyclic (~1024 g/mol) and also activates MC3R and MC4R. The two are not interchangeable in a protocol.
Is the product analyzed?
Yes. Each batch is analyzed by HPLC and accompanied by an independent Certificate of Analysis (COA) specific to the batch.
In what form is it delivered?
In the form of a white lyophilized powder in a sealed 10 mg bottle, to be reconstituted with bacteriostatic water.
How is it stored?
The powder should be stored away from light, and the reconstituted solution in the refrigerator. Melanocortin analogues are sensitive to light.
What is this product intended for?
For scientific research in the laboratory only. It is not intended for human or animal consumption, nor for therapeutic, cosmetic or tanning use.
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