SNAP-8 10 mg

SNAP-8 10 mg — acetylated octapeptide, SNARE complex modulator

Le SNAP-8 (Acetyl Octapeptide-3, also designatedAcetyl Glutamyl Heptapeptide-1) is asynthetic octapeptidewhich replicates the N-terminal end of the proteinSNAP-25It is being studied for its ability to compete with this protein during the assembly of theSNARE complexBottle of10 mg lyophilizedintendedexclusively for laboratory research.

Product features

• Compound :SNAP-8 / Acetyl Octapeptide-3, acetylated and amidated octapeptide
• Sequence :Ac-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp-NH2 (8 amino acids)
• Molar mass:approximately 1075 g/mol
• Quantity :10 mg per vial, lyophilized (powder to be reconstituted)
• Purity:controlled by HPLC, result on the batch certificate
• Quality control:Independent COA per batch
• Presentation :sealed bottle, crimped cap, white lyophilized powder

Scientific context

The release of neurotransmitters at the neuromuscular junction depends on theSNARE complex, an assembly of three proteins —SNAP-25, theresyntaxin-1and theVAMP / synaptobrevin— which anchors the vesicles to the membrane and triggers their fusion.

SNAP-8 incorporates the first eight residues from the N-terminal end of SNAP-25. In published models, this homology allows it to enter intocompetitionwith the endogenous protein at the time of complex assembly, and thus modulate vesicular exocytosis. This is whatmolecular mechanismwhich is the subject of the available work — essentiallyin vitroand on topical formulations.

SNAP-8 and Argireline: two lengths, the same sequence initiation

The SNAP-8 is the direct continuation of theArgireline(Acetyl Hexapeptide-3): it shares thefirst six residuesand addstwo amino acids, an alanine and an aspartic acid. This elongation modifies the peptide's affinity for the SNARE complex assembly site — this is the very reason for its design.

The two compounds are therefore related butthey are not interchangeableneither the complete sequence nor the molar mass coincide, and a protocol written for one cannot be transposed to the other.

Reconstruction and conservation

The bottle contains a freeze-dried powder to be reconstituted withbacteriostatic water, available separately. SNAP-8 is soluble in aqueous solution. The powder should be stored in a freezer and protected from light; the reconstituted solution should be stored in a refrigerator. Avoid repeated freezing/thawing cycles: themethioninepresent in the sequence is sensitive to oxidation.

Quality and analysis

Each batch is analyzed byHPLCwith aIndependent Certificate of Analysis (COA)specific to the batch. The purity is that indicated on the certificate.

Delivery

Shipping within 24 to 48 hours from our stock in France.3 to 5 business days, with follow-up. Direct sale without intermediaries — that's what allows the advertised price.

What this product is not

The SNAP-8 issold here as a laboratory reagent, and nothing elseThis is notneither a medicine, nor a cosmetic, nor a ready-to-use finished productand is in no way an alternative to a botulinum toxin injection: the two have neither the same mechanism, nor the same regulatory status, nor the same safety profile. It is notnot intended for human or veterinary useThis product is not intended for diagnostic or therapeutic use, and no instructions for use, dosage, or administration protocol are provided. The buyer is solely responsible for complying with applicable regulations in their country.

Frequently Asked Questions

What is the SNAP-8?
SNAP-8 (Acetyl Octapeptide-3) is a synthetic octapeptide that replicates the N-terminal end of the SNAP-25 protein, studied in research for its competition with it in the assembly of the SNARE complex.

What is the difference with Argireline?
Length. Argireline (Acetyl Hexapeptide-3) has six amino acids; SNAP-8 has eight, the same six plus alanine and aspartic acid. Related sequences, distinct compounds, not interchangeable in a protocol.

Is the product analyzed?
Yes. Each batch is analyzed by HPLC and accompanied by an independent Certificate of Analysis (COA) specific to the batch.

In what form is it delivered?
In the form of a white lyophilized powder in a sealed 10 mg bottle, to be reconstituted with bacteriostatic water.

How is it stored?
The powder should be stored in a freezer away from light, and the reconstituted solution in a refrigerator. Avoid repeated freezing and thawing, as the methionine in the sequence is sensitive to oxidation.

What is this product intended for?
For scientific research in the laboratory only. It is not intended for human or animal consumption, nor for therapeutic or cosmetic use.

Product intended exclusively for scientific laboratory research. Not intended for human or animal consumption, nor for medical, veterinary, or therapeutic use. Sale strictly reserved for adults (18 years and older).