Selank and Semax come from the same institute in Moscow and share the same chemical mechanism. They are often mentioned together, but they do not study the same thing. This guide compares their origin, their structure, what research says about them, and our analyses.
Selank 10 mg – €49.90Semax 10 mg – €49.90
The essentials
Selank and Semax side by side
| Selank | Semax | |
|---|---|---|
| Derived from | SelankTuftsin (immunoglobulin fragment) | SemaxACTH (4-10), hormone fragment |
| Sequence | SelankThr-Lys-Pro-Arg-Pro-Gly-Pro | SemaxMet-Glu-His-Phe-Pro-Gly-Pro |
| CAS NO. | Selank129954-34-3 | Semax80714-61-0 |
| Molar mass | Selank751.9 g/mol | Semax813.9 g/mol |
| Main research focus | SelankAnxiety, GABA system, serotonin | SemaxCognition, neuroprotection, BDNF |
| Janoshik Report | Selank#223456 : 99,68 % | Semax#229265 : 99,33 % |
| Price (10 mg) | Selank49,90 € | Semax49,90 € |
The Selank
The Selank departs from thetuftsine(Thr-Lys-Pro-Arg), a small immune system peptide, is extended by Pro-Gly-Pro for a longer duration. Research, conducted primarily in Russia, focuses on its anxiolytic-like activity observed in animals, its effects on GABA transmission, serotonin, and the expression of neurotrophic factors. Most publications are Russian and involve small sample sizes.
The Semax
Semax takes up fragment 4-10 of theACTHThe hormone that stimulates the adrenal glands is also prolonged by Pro-Gly-Pro. It has lost the hormonal effect of ACTH: this is precisely what interests researchers. Their work focuses on the expression of BDNF and NGF (neuronal growth factors), neuroprotection, and synaptic plasticity.
The two peptides are not interchangeable: they do not have the same origin or the same research focus.
Status
| Question | Response by 01/11/2026 |
|---|---|
| QuestionAre they considered medicines in France? | Response by 01/11/2026No, neither in France nor in the European Union. |
| QuestionAnd in Russia? | Response by 01/11/2026Yes, both are registered there as medicines, in the form of nasal drops. |
| QuestionIn what form are they sold here? | Response by 01/11/2026In lyophilized powder form, as research reagents, without medical use. |
Our Janoshik analysis
| Report | Product | Batch | Analysis | Quantity measured | HPLC Purity | Key |
|---|---|---|---|---|---|---|
| Report#223456 | ProductSelank 10 mg | BatchMP-777SK101 | Analysis25/08/2026 | Quantity measured11.93 mg | HPLC Purity99,68 % | Key9KTJRGRM4VUR |
| Report#229265 | ProductSemax 10 mg | BatchMP-777SMX101 | Analysis15/09/2026 | Quantity measured10.67 mg | HPLC Purity99,33 % | KeyJKNPVEKJMX1E |
The keys are verified at janoshik.com/verify: the original report is displayed from the laboratory's website.
Single bottle or spray bottle pack
| Product | Content | Price |
|---|---|---|
| ProductSelank 10 mg | Content10 mg vial, lyophilized powder | Price49,90 € |
| ProductSemax 10 mg | Content10 mg vial, lyophilized powder | Price49,90 € |
| ProductSelank Spray Pack | ContentSelank 10 mg, sterile saline solution, reconstitution syringe, empty spray bottle, gloves, swabs | Price59,90 € |
| ProductSemax Spray Pack | ContentSemax 10 mg, sterile saline solution, reconstitution syringe, empty spray bottle, gloves, swabs | Price59,90 € |
The bottle alone is reconstituted withbacteriostatic water(method inreconstitute a lyophilized peptideIn powder form, it should be kept in the refrigerator or freezer; in solution, in the refrigerator, away from light.
Frequently Asked Questions
What is the difference between Selank and Semax?
Selank is derived from tuftsin and is primarily studied for anxiety; Semax is derived from a fragment of ACTH and is studied for cognition and neuroprotection. Both end with Pro-Gly-Pro, which stabilizes them.
What is Selank?
A synthetic heptapeptide (Thr-Lys-Pro-Arg-Pro-Gly-Pro) developed at the Institute of Molecular Genetics in Moscow, an analogue of tuftsin, is being studied for its anxiolytic-like activity in animals.
Are Selank and Semax medications?
They are registered as medicines in Russia, but not in France or the European Union, where they are sold as research reagents.
What does the Selank Spray Pack contain?
A bottle of lyophilized Selank 10 mg, sterile physiological saline, a reconstitution syringe, an empty spray bottle, gloves and disinfectant swabs, for €59.90.
Are PeptiLine's Selank and Semax analyzed?
Yes: Selank 99.68% (Janoshik report #223456, lot MP-777SK101) and Semax 99.33% (report #229265, lot MP-777SMX101), verifiable at janoshik.com/verify.
- DSIP: the guide— discovery, state of sleep research, conservation
- Selank and Semax— Two Russian heptapeptides compared, Janoshik analysis (you are here)
- Bacteriostatic water— the reconstitution solvent explained
- Reconstitute a lyophilized peptide— the step-by-step manipulation in the laboratory
- Neuro & Sleep— all peptides in the category
- Certificates of analysis— all the Janoshik reports, with their key
Institute of Molecular Genetics, Russian Academy of Sciences; PubChem CID 11765600 (Selank) and 9811102 (Semax); Janoshik reports #223456 and #229265; status as of 01/11/2026. PeptiLine products are intended exclusively for scientific laboratory research. This page does not provide medical advice, protocols, or dosage information.